卵巢颗粒细胞瘤是相对少见的卵巢性索间质细胞肿瘤,因发病初期多有内分泌相关症状,而使得该肿瘤容易被早期发现。各种分子生物学指标在该病的诊断及随访中发挥着重要的作用。手术是其重要的治疗措施,化疗、放疗、激素治疗及分子生物靶向治疗也是重要的治疗方法。对这类患者采取合理的治疗手段,相对于其他的卵巢恶性肿瘤,可以达到较高的存活率。 Ovarian granulosa cell tumor is a relatively rare ovarian cord stromal tumor, early onset due to more endocrine-related symptoms, which makes the tumor easily be found early. Various molecular biological indicators play an important role in the diagnosis and follow-up of the disease. Surgery is an important treatment. Chemotherapy, radiotherapy, hormonal therapy and molecular biological therapy are also important treatments. A reasonable treatment for such patients, compared with other ovarian cancer, can achieve a higher survival rate.