论文部分内容阅读
目的:探讨精液中白细胞对精液各主要参数的影响。方法:回顾性分析216例男性不育患者的精液质量,根据WHO推荐的方法进行精液常规及精子形态学分析,利用联苯胺法进行白细胞检测,并将患者分为白细胞精子症(>1×106/mL)和非白细胞精子症(≤1×106/mL)两组。结果:与非白细胞精子症组(n=152)相比,白细胞精子症组(n=64)的精子密度明显降低[(38.36±23.16)×106/mL vs(47.14±19.70)×106/mL,P<0.01],活动率明显下降(43.50%±11.49%vs 48.17%±10.28%,P<0.01),a+b级精子比率明显下降(31.00%±10.64%vs 35.87%±10.66,P<0.01),正常形态精子百分率明显降低(10.75%±4.40%vs 12.31%±3.84%,P<0.05),而白细胞精子症组的精液液化异常发生率较非白细胞精子症组明显增高(14.06%vs 4.61%,P<0.05)。结论:白细胞精子症可导致精子密度、活动率及正常形态精子百分率的降低,并可引起精液液化异常发生率的增高。
Objective: To investigate the influence of semen leukocyte on the main parameters of semen. Methods: A retrospective analysis of 216 cases of male infertility semen quality, according to WHO recommended methods for sperm routine and sperm morphology analysis, the use of benzidine method for leukocyte detection, and the patients were divided into leukocyte spermatogenesis (> 1 × 106 / mL) and non-leukocyte spermatogenesis (≤1 × 106 / mL). Results: Compared with non-leukocyte sperm group (n = 152), sperm density in leukocyte sperm group (n = 64) was significantly lower than that in non-leukocyte sperm group [(38.36 ± 23.16) × 106 / mL vs (47.14 ± 19.70) × 106 / mL , P <0.01]. The activity of a + b sperm decreased significantly (43.50% ± 11.49% vs 48.17% ± 10.28%, P <0.01) 0.01). The percentage of normal spermatozoa decreased significantly (10.75% ± 4.40% vs 12.31% ± 3.84%, P <0.05), while the abnormal rate of sperm liquefaction in leukocyte sperm group was significantly higher than that in non-leukocyte sperm group (14.06% vs 4.61%, P <0.05). CONCLUSIONS: Leukocyte spermatogenesis can lead to a decrease in sperm concentration, motility, and percentage of normal spermatozoa, and can cause an increased incidence of abnormal semen liquefaction.