采用组织胺诱导脉鼠皮肤局部搔痒及右旋糖酥诱导小鼠全身搔痒模型，研究麻黄连翘赤小豆汤及加减方的止痒作用，结果表明，二者对两种模型动物均有显著的抑制搔痒反应的作用。加减方虽然优于原方，但是二者之间没有显著性差异。方中主要药物麻黄的有效成分麻黄碱也有显著的止痒作用。 Histamine was used to induce itching in rat skin and dextrose cake-induced systemic itching in mice to study the antipruritic effects of Mahuang Lianqiao Chixiaodou Decoction and addition and subtraction prescriptions. The results showed that both of them had significant effects on the two model animals. Inhibit the effects of pruritic reactions. Although the addition and subtraction is better than the original, there is no significant difference between the two. Ephedrine, the active ingredient of the main drug ephedra, also has a significant antipruritic effect.