论文部分内容阅读
目的研究体温干预在婴幼儿体外循环手术中对快通道的影响。方法临床纳入318例我院2015年4月至2016年6月期间行体外循环手术(CPB)的患儿作为研究对象。根据随机数字表法分为两组各159例。其中159例患儿术中采用体温干预作为干预组,另159例患儿术中未实施体温干预作为对照组。观察两组患儿不同时段凝血功能变化情况,分析患儿手术结束至复苏后拔管时间。结果麻醉诱导后两组患儿PT、APTT以及TT水平对比差异无统计学意义,P>0.05;应用肝素时以及手术结束后干预组患儿PT、APTT以及TT水平与对照组相比差异有统计学意义,P<0.05。干预组患儿手术结束至复苏后拔管时间平均为(31.2±8.9)min,小于对照组的(43.2±10.2)min,P<0.05。结论体温干预可有效维持体外循环手术患儿凝血功能,减少术后出血情况,促进患儿苏醒和预后效果,值得临床应用及推广。
Objective To study the effect of body temperature intervention on fast track during infantile cardiopulmonary bypass. Methods A total of 318 children undergoing cardiopulmonary bypass (CPB) during our hospital from April 2015 to June 2016 were enrolled in this study. According to random number table divided into two groups of 159 cases. Among them, 159 cases were treated with body temperature intervention as the intervention group and 159 cases with no intervention during the operation as the control group. The changes of coagulation function at different time points in both groups were observed. The extubation time from the end of operation to the recovery was analyzed. Results There was no significant difference in the levels of PT, APTT and TT between the two groups after induction of anesthesia (P> 0.05). The differences of PT, APTT and TT levels between the intervention group and the control group were statistically significant Significance, P <0.05. The average extubation time from the end of operation to resuscitation in intervention group was (31.2 ± 8.9) min, which was less than that in control group (43.2 ± 10.2) min, P <0.05. Conclusion Body temperature intervention can effectively maintain the blood coagulation function of children undergoing cardiopulmonary bypass, reduce the postoperative bleeding, and promote the recovery and prognosis of children. It is worthy of clinical application and promotion.