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近几年来,我们治疗细菌性痢疾常首选复方新诺明口服,取得较为满意的疗效,但在应用复方新诺明后,有5例患者出现严重精神神经症状。现报告于后:【例1】王××,男,8岁。脓血便伴里急后重三天,于1980年7月12日来我院门诊就医。患儿不发烧,日大便10余次,就诊前来服过药。检查:精神尚可,无脱水征,心肺未见异常,腹软,左下腹轻度压痛,肠鸣音稍亢进。大便镜检:脓细胞(+++),红细胞(++),诊断:急性细菌性痢疾。应用复方新诺明合并苏打各一片,每日两次口服,用药4次后,患儿大便外观不带脓血,自觉里急后重消失,但家长发现患儿躁动不安、哭叫、伸舌、流口水、头向上后仰、两眼上翻、卧位时呈角弓反张样,急来院复诊。检查:体温36.5℃,脉
In recent years, we are often the first choice for the treatment of bacterial dysentery, cotrimoxazole oral administration, and achieved satisfactory results, but after the application of cotrimoxazole, there are 5 patients with severe neuropsychiatric symptoms. Now report after: [Example 1] Wang × ×, male, 8 years old. Pus and blood will be accompanied by tenesmus heavy three days, July 12, 1980 to our hospital for medical treatment. Children do not have fever, stool more than 10 times, to come to medicine before treatment. Check: the spirit can be, no signs of dehydration, no abnormal heart and lung, abdominal soft, mild left lower quadrant tenderness, bowel sounds slightly hyperthyroidism. Stool microscopy: pus (+++), red blood cells (++), diagnosis: acute bacillary dysentery. The application of compound norepine merged with soda each one twice daily oral medication 4 times, the appearance of children with stool without purulent blood, consciously tenesmus and disappear, but parents found that children with restlessness, cries, stretch tongue, drooling , Head back up, his eyes turned upside down when the angle was arch anti-Zhang Xing, anxious to referral hospital. Check: body temperature 36.5 ℃, pulse