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目的探讨以早期强化血液净化联合胃肠道灌洗为主要手段的综合治疗方法抢救百草枯农药(PQ)中毒的临床疗效。方法本院重症医学一科(SICU)自2012年4月至2012年11月收治16例口服百草枯农药中毒患者,均应用以早期强化血液净化联合胃肠道灌洗为主要手段的综合治疗方法进行抢救,观察患者转归。结果 5例患者抢救成功治愈出院,5例患者院内死亡,6例患者放弃治疗主动出院后死亡。接受院内综合治疗患者治愈率为50.0%,较传统方法抢救成功率大幅提升。结论早期彻底的胃肠道灌洗并灵活运用各种强化血液净化方式有助于提高百草枯中毒患者的抢救成功率,是一种理想有效的抢救方法。
Objective To investigate the clinical efficacy of salvage paraquat pesticide (PQ) poisoning with the comprehensive treatment of early intensive blood purification combined with gastrointestinal lavage. Methods A total of 16 patients with oral paraquat pesticide poisoning were admitted to our department of SICU from April 2012 to November 2012. All of the patients were treated with the combination of early intensive blood purification and gastrointestinal lavage To rescue, observe the patient outcome. Results Five patients were successfully treated and discharged. Five patients died in the hospital and six patients died after giving up treatment. The hospital received comprehensive treatment of patients cure rate was 50.0%, compared with the traditional method of rescue success rate increased significantly. Conclusion Early and thorough gastrointestinal lavage and flexible use of various methods of intensive blood purification help to improve the rescue success rate of paraquat poisoning patients is an ideal and effective rescue method.