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目的:观察米非司酮联合依沙吖啶终止中期妊娠的临床效果及安全性。方法:选择15~27周要求终止妊娠的妇女200例,随机分成观察组和对照组,两组均经腹壁羊膜腔注射依沙吖啶100 m g,观察组加服150 m g,观察两组引产效果及安全性。结果:两组引产成功率均为100%,观察组注药至宫缩,宫缩至胎儿娩出时间均明显短于对照组(P<0.01);产后2 h出血量及胎盘,胎膜残留率明显低于对照组(P<0.05)。结论:米非司酮联合依沙吖啶终止中期妊娠引产时间短,产后出血少,清宫率低,是安全、有效的方法。
Objective: To observe the clinical efficacy and safety of mifepristone combined with ethacridine in stopping mid-term pregnancy. Methods: A total of 200 women who required termination of pregnancy between 15 and 27 weeks were randomly divided into observation group and control group. Both groups were injected with 100 mg of ethacridine via the amniotic cavity in the abdominal wall and 150 mg in the observation group. The effects of induction of labor And safety. Results: The success rate of induction of labor in both groups was 100%. The observation group was injected with contractions to contractions and contractions to fetus was significantly shorter than the control group (P <0.01); 2 h postpartum hemorrhage and placenta, fetal membrane residual rate Significantly lower than the control group (P <0.05). Conclusion: Mifepristone combined with ethacridine termination of short-term induction of labor in midterm pregnancy, less postpartum hemorrhage, clearance rate is low, is a safe and effective method.