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目的:探讨血栓通辅助治疗老年脑梗死后遗症的临床疗效以及对患者生活质量的干预作用。方法:老年脑梗死后遗症患者126例按入院先后顺序分为对照组和观察组。对照组患者在常规治疗基础上予脑水蛋白水解物注射液。观察组在对照组的基础上再加用血栓通注射液,两组疗程均为4周。观察两组患者的临床疗效和药品不良反应,评价比较两组患者的日常生活自理能力及生活质量。结果:观察组治疗总有效率为93.65%,明显高于对照组的71.24%(P<0.05)。治疗后两组患者的神经功能损伤评分及汉密尔顿抑郁程度评分均较治疗前明显降低(P<0.01),且观察组患者明显低于对照组(P<0.01)。治疗后,两组患者的各项生活质量评分均明显升高(P<0.05),两组间差异无统计学意义(P>0.05)。治疗过程中两组患者均未见严重药品不良反应。结论:血栓通辅助治疗老年脑梗死后遗症疗效显著,能有效改善患者生活质量,且安全性较好。
Objective: To investigate the clinical efficacy of Xueshuantong in the treatment of sequelae of senile cerebral infarction and its effect on the quality of life of patients. Methods: 126 cases of senile cerebral infarction patients were divided into control group and observation group according to the order of admission. Patients in the control group received hydrocephalite injection on a routine basis. Observation group on the basis of the control group plus Xueshuantong injection, two courses were 4 weeks. The clinical efficacy and adverse drug reactions of the two groups were observed. The self-care ability and quality of life of the two groups were compared. Results: The total effective rate of the observation group was 93.65%, which was significantly higher than that of the control group (71.24%, P <0.05). After treatment, the scores of neurological impairment and Hamilton depression in both groups were significantly lower than those before treatment (P <0.01), and the patients in the observation group were significantly lower than those in the control group (P <0.01). After treatment, the quality of life scores of both groups were significantly increased (P <0.05), and there was no significant difference between the two groups (P> 0.05). Two groups of patients in the course of treatment were not serious adverse drug reactions. Conclusion: Xueshuantong treatment of senile cerebral infarction sequelae effect is significant, can effectively improve the quality of life of patients with better safety.