本文作者报道了伯喹对幼年猎兔犬、猕猴及幼小大鼠的亚急性毒性。采用新鲜配制的二磷酸伯喹水溶液给动物灌胃,药物剂量均以基质量表示,疗程28天。在给药期间每天称体重调整药量、观察动物的行为变化及中毒症状,定期检查血、尿、粪。实验结束时将动物解剖作组织学观察。犬:16只,雌、雄各半,均分为4组,第1、2、3组分别喂伯喹1、3及9mg/kg/天,第4 The authors report subacute toxicity of beequin to young beagle dogs, macaques and young rats. Freshly prepared primary aqueous solution of diphosphate diphosphate to animals fed gavage, the drug dose are based on the mass of the base, the course of 28 days. During the administration of daily dose adjustment body weight, observation of animal behavior changes and symptoms of poisoning, regular examination of blood, urine and feces. At the end of the experiment, the animals were dissected for histological observation. Dogs: 16, female and male half, were divided into 4 groups, 1, 2, 3 were fed Puerarin 1,3 and 9mg / kg / day, the first 4