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为了了解系统性红斑狼疮患者血清中补体（C3、C4及B因子）在疾病的发病及进程中的仓量变化及其关系。采用速率散射比法法对红斑狼疮活动期与稳定期患者各50例血清中的补体C3、C4及B因子进行检测。结果显示；活动期C3、C4及B因子降低均有极显著意义（P＜0．001）；稳定期C3、C4含量虽有所回升但与对照组相比仍有显著降低（P＜0．001），而B因子基本回复到正常水平（P＞0，05）。认为，血清中补体含量在整个病程的降低可作为系统性红斑狼疮患者诊断的免疫学依据，而B因子在疾病稳定后最早回复正常这一特点，可作为判断病期及疗效观察的有用指标。
In order to understand the changes of serum levels of complement (C3, C4 and B factors) in the pathogenesis and progression of systemic lupus erythematosus and its relationship. The rate scatter ratio method was used to detect complement C3, C4 and factor B in serum of 50 patients with active and stable lupus erythematosus. The results showed that the activity of C3, C4 and B factors were significantly reduced (P <0.001); stable phase C3, C4 levels although the rise but still significantly lower than the control group (P <0. 001), while the B factor returned to normal (P> 0,05). That serum complement levels in the course of the whole course of the disease can be used as a diagnosis of systemic lupus erythematosus immunological basis, and B factor in the stable state of the earliest return to normal after this feature can be used as a useful indicator to determine the duration and efficacy of observation.