目的　了解广州市城乡中年人群的体力活动状况及其与心血管病主要危险因素的关系。方法　采用整群随机抽样方法调查广州市 35～ 5 9岁城市居民 112 4人及农村居民 10 2 9人 ,按照国家“九五”攻关课题 (编号 96 - 90 6 - 0 2 - 0 1)统一方案、采用标准化方法进行。结果　农村人群中等强度及以上的体力活动时间平均占全天的 2 0 7% ,明显高于城市人群 (7 2 % ) ;农村人民不活动或少活动的时间占全天的 6 0 5 % ,较城市人群 (73 7% )少。农村人群高胆固醇现患率、高密度脂蛋白胆固醇降低率、高血糖现患率和超重率均低于城市人群 ,但吸烟率和饮酒率明显高于城市人群。多元线性回归分析显示 ,不活动和少活动时间对血压升高、血中胆固醇升高、高密度脂蛋白胆固醇降低及体重增加的影响均有非常显著性意义。结论　缺乏体力活动会使心血管病危险因素有增加的趋势 Objective To understand the physical activity of middle-aged and urban residents in urban and rural areas of Guangzhou and its relationship with the major risk factors of cardiovascular disease. Methods A total of 1,124 urban residents aged 35-59 and 10,29 rural residents were surveyed by cluster random sampling method in accordance with the national “ninth five-year plan” (No. 96-906-0102-0) Program, using standardized methods. Results The average intensity of physical activity in rural areas was 20.7% of the whole day, which was significantly higher than that of the urban population (72%). The inactive or less active people in rural areas accounted for 65.5% of the whole day, Less than the urban population (73.7%). The incidence of high cholesterol, HDL cholesterol, prevalence of hyperglycemia and overweight in rural population were lower than those in urban areas, but smoking and drinking rates were significantly higher in urban areas than in urban areas. Multivariate linear regression analysis showed that inactive and less active time had a very significant effect on blood pressure, elevated blood cholesterol, reduced HDL cholesterol and weight gain. Conclusion The lack of physical activity will increase the risk factors for cardiovascular disease