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随访观察56例心肌梗塞患者长期服用美多心安对血脂、血糖和心功能的影响,服药6个月以上,每日100mg,平均砚察16.8±4.6个月。前后对比,结果表明心功能临床改善者占30.8％;收缩压、舒张压和心率较治疗前明显下降。彩色多普勒超声血流显象示心排血量(CO)和二尖瓣口E峰和A峰流速比值(VE/VA)无明显变化。36例血脂分析中,胆固醇(TC)水平较治疗前明显升高,其中男性29例TC亦明显升高,而女性7例三酸甘油酯升高,血糖无明显变化。
The follow-up observation of 56 patients with myocardial infarction long-term use of Metoprolol on blood lipids, blood glucose and cardiac function, taking more than 6 months, daily 100mg, an average of 16.8 ± 4.6 months of observation. Before and after comparison, the results showed that clinical improvement of cardiac function accounted for 30.8%; systolic blood pressure, diastolic blood pressure and heart rate decreased significantly compared with before treatment. Color Doppler flow imaging showed no significant change in cardiac output (CO) and mitral E and A peak flow velocity ratio (VE / VA). In the 36 cases of blood lipid analysis, the level of cholesterol (TC) was significantly higher than that before treatment, including 29 cases of male TC was significantly increased, while the female 7 cases of triglyceride increased, no significant changes in blood glucose.