视网膜母细胞瘤(简称RB),亦称视网膜胶质瘤。是学龄前儿童常见的眼科多发肿瘤,3～4岁为高发年龄。RB多为散发型,遗传型少见,两代发病直接遗传国内报道3例。我所近期收治一例母子双眼RB,其母右眼球摘除术后放疗,左眼未治自发退行,视力恢复正常,现已存活27年。现将二人情况报道如下。 Retinoblastoma (RB), also known as retinal glioma. It is a common ophthalmic multiple tumor in preschool children. The age of 3 ~ 4 years old is high. RB mostly sporadic, rare genotypes, two generations of direct reports of genetic disease in China 3 cases. I recently admitted to a case of mother and child binocular RB, the mother of his right eye after radical surgery radiotherapy, left eye did not rule out spontaneous regression, visual acuity returned to normal, has now survived 27 years. The two are now reported as follows.