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目的对就诊于北京协和医院痛风门诊的青年痛风患者的临床特点进行分析。方法对2008年1月至2012年2月就诊于协和医院普通内科痛风门诊的324例痛风患者进行问卷调查和临床资料收集,并将资料录入痛风门诊患者数据库管理系统并分析,以了解该人群的临床特点,初步探讨青年患者的人群特征。结果本组324例中,男316例(97.5%),女8例(2.5%),平均病程(100±77)个月,血清尿酸平均值(585.0±123.2)μmol/L,多关节受累多见,占79%;青年组较中老年组病程更短(P<0.05),基础疾病合并率更低(P<0.05),但尿酸水平[(601.5±11.2)μmol/L]较中老年组[(569.7±11.1)μmol/L]更高(P<0.05),累及关节数与中老年组差异无统计学意义。结论痛风患者人群更加年轻化,临床特征更具复杂性,青年患者所为一个独特人群需要给予足够的重视。
Objective To analyze the clinical features of young gout patients attending gout clinic in Peking Union Medical College Hospital. Methods A total of 324 gout patients attending the General Internal Medicine Gout Clinic of Peking Union Medical College Hospital from January 2008 to February 2012 were investigated by questionnaires and clinical data. The data were entered into the Gout Outpatient Database Management System and analyzed to understand the Clinical characteristics, preliminary study of the characteristics of the population of young patients. Results Among the 324 patients, 316 (97.5%) were males and 8 (2.5%) females, with an average duration of (100 ± 77) months, mean serum uric acid (585.0 ± 123.2) μmol / L, (601.5 ± 11.2) μmol / L] than those in the middle-aged and elderly groups (79%). The youth group had a shorter duration of disease (P <0.05) and a lower rate of underlying disease (P0.05) [(569.7 ± 11.1) μmol / L] (P <0.05). There was no significant difference in the number of joints involved and the middle-aged and elderly patients. Conclusions The population of gout patients is younger and their clinical features are more complex. The young patients need to pay enough attention to them as a unique group of people.