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川崎病(KD)是好发于5岁以下儿童的以全身血管炎为主要病理改变的自身免疫性疾病,主要临床特征为持续发热、球结膜充血、唇及口腔黏膜改变、手足指端脱屑、皮疹、颈淋巴结肿大等,而血管炎的病理改变可累及小血管、中等肌性动脉及全身各个脏器,其中以冠状动脉损害最为突出.研究[1]结果显示,未给予及时诊断与治疗的KD患儿中约15%~30%发生冠状动脉扩张或冠状动脉瘤形成.流行病学调查[2]结果显示,KD发病率呈逐年升高趋势,
Kawasaki disease (KD) is an autoimmune disease mainly caused by systemic vasculitis, which occurs in children under 5 years of age. The main clinical features are persistent fever, conjunctival hyperemia, lip and oral mucosal changes, , Rash, cervical lymph node enlargement, etc., and the pathological changes of vasculitis can affect the small blood vessels, the middle muscular artery and the various organs of the body, of which the most prominent coronary artery damage.Research [1] results showed that did not give timely diagnosis and About 15% to 30% of children with KD underwent coronary artery dilatation or coronary aneurysm formation.According to the epidemiological survey [2], the incidence of KD is increasing year by year,