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反义寡聚核苷酸(antisense oligonucleotides,AS-ODNs)的概念最先提出于1967年,经过30多年的研究,人们已意识到在各种反义寡聚核苷酸的广阔领域里,有可能寻找到更有效的抗病毒和抗肿瘤新药。
The concept of antisense oligonucleotides (AS-ODNs) was first proposed in 1967. After more than 30 years of research, it has been recognized that in a broad range of antisense oligonucleotides, there are May find more effective anti-virus and anti-tumor drugs.