THE CALCULATION OF CHEMICAL SHIFTS IN DISUBSTITUTED NAPHTHALENES

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The principle and method for calculating the chemical shifts of substituted benzenes have been extended to the calculation of chemical shifts in disubstituted naphthalenes. We have set up a series of empirical parameters for the calculation of chemical shifts. The calculated results of 439 8 values from 78 compounds show that the standard deviation between the calculated and the experimental values is 0.08 ppm. The combination of this calculation with that of the coupling constants can be used to provide a criterion .for the determination of molecular structure in disubstituted naphthalenes as well as to assign NMR parameters for the experiment of proton simulated spectra of disubstituted naphthalenes. The principle and method for calculating the chemical shifts of substituted benzenes have been extended to the calculation of chemical shifts in disubstituted naphthalenes. We have set up a series of empirical parameters for the calculation of chemical shifts. The calculated results of 439 8 values ​​from 78 compounds show that the standard deviation between the calculated and the experimental values ​​is 0.08 ppm. The combination of this calculation with that of the coupling constants can be used to provide a criterion. for the determination of molecular structure in disubstituted naphthalenes as well as to assign NMR parameters for the experiment of proton simulated spectra of disubstituted naphthalenes.
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