Many of the Yanshannian intermediate-acid intrusive rocks related to Cu-Au mineraliza-tion in the Eastern Yangtze Block are characterized by high Al2O3, Sr contents, while low in Y, Yb contents, thus with high Sr/Y, and La/Yb ratios, and variational isotope signatures in particular, e.g. e Nd( t ) = -11.92—1.96, (143Nd/144Nd)i = 0.5120—0.5125, TDM = 0.70—1.71 Ga, (87Sr/86Sr)i = 0.7043—0.7076. The geochemical characteristics of these rocks suggest that: (1) these rocks are geo-chemically similar to adakite, which might have been stemmed from the partial melting of thick-ened basaltic lower crust due to basalt underplating; and (2) the high pressure (1.2—4.0 GPa) and high temperature (850—1150℃) surroundings of the lower crust favor both the fluid and ada-kite-like magma to generation. Not only can the adakite-like magma carry abundant fluid and Cu-Au ore-froming materials, but also can it bring them to the shallow part with ease and contrib-utes to the Cu-Au mineralization. Many of the Yanshanian intermediate-acid intrusive rocks related to Cu-Au mineralization-in the Eastern Yangtze Block are characterized by high Al2O3, Sr contents, while low in Y, Yb contents, thus with high Sr / Y, and La / Yb ratios, and variational isotope signatures in particular, eg e Nd (t) = -11.92-1.96, (143Nd / 144Nd) i = 0.5120-0.5125, TDM = 0.70-1.71 Ga, (87Sr / 86Sr) i = 0.7043-0.7076. These geochemical characteristics of these rocks suggest that: (1) these rocks are geo-similar to adakite, which might have stemmed from the partial melting of thick-ened basaltic lower crust due to basalt underplating; and (2) the high pressure (1.2-4.0 GPa) and high temperature (850-1150 ° C) surroundings of the lower crust favor both the fluid and ada-kite-like magma to generation. Not only can the adakite-like magma carry abundant fluid and Cu-Au ore -froming materials, but also can it it bring them to the shallow part with ease and contrib-utes to the Cu-Au mineralization .