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目的:观察扶正解毒祛湿汤联合重组人干扰素治疗宫颈人乳头瘤病毒(human papillomavirus,HPV)感染的临床疗效。方法:选择90例宫颈HPV感染患者随机分为治疗组和对照组。治疗组45例应用扶正解毒祛湿汤联合干扰素治疗,对照组45例应用干扰素治疗。治疗3个疗程后比较两组HPV转阴情况、宫颈糜烂样改变情况。结果:总有效率治疗组为80.0%,对照组为66.7%,组间比较,差异有统计学意义(P<0.05);宫颈糜烂样改变总有效率治疗组为87.5%,对照组为67.5%,组间比较,差异有统计学意义(P<0.05)。结论:扶正解毒祛湿汤联合重组人干扰素治疗宫颈HPV感染和宫颈糜烂样改变有显著疗效。
Objective: To observe the clinical effect of Fuzheng Jiedu Qushi Decoction combined with recombinant human interferon on the treatment of cervical papillomavirus (HPV) infection. Methods: Ninety patients with cervical HPV infection were randomly divided into treatment group and control group. In the treatment group, 45 cases were treated with Fuzheng Jiedu Decoction combined with interferon, and 45 cases in the control group were treated with interferon. After 3 courses of treatment, the situation of negative conversion of HPV and cervical erosion were compared between the two groups. Results: The total effective rate was 80.0% in the treatment group and 66.7% in the control group, the difference was statistically significant (P <0.05); the total effective rate of cervical erosion was 87.5% in the treatment group and 67.5% in the control group , The difference between the two groups was statistically significant (P <0.05). Conclusion: Fuzheng Jiedu Qushi Decoction combined with recombinant human interferon in the treatment of cervical HPV infection and cervical erosion-like changes have a significant effect.