【摘 要】
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目的 评价胺碘酮联合美托洛尔治疗快速心律失常的疗效及安全性.方法 66例快速心律失常患者,随机分为对照组与观察组,各33例.对照组采用胺碘酮治疗,观察组采用碘酮联合美托洛
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目的 评价胺碘酮联合美托洛尔治疗快速心律失常的疗效及安全性.方法 66例快速心律失常患者,随机分为对照组与观察组,各33例.对照组采用胺碘酮治疗,观察组采用碘酮联合美托洛尔治疗.比较两组患者的治疗效果、不良反应发生情况以及治疗后心率和血压水平.结果 观察组治疗总有效率为96.97％,显著高于对照组的66.67％,差异具有统计学意义(χ2=10.185,P0.05).两组患者均未出现严重不良反应,且经过对症处理后均已消失.治疗后,对照组和观察组舒张压分别为(97.75±7.58)、(82.36±6.53)mm Hg(1 mm Hg=0.133 kPa),收缩压分别为(147.71±9.42)、(132.66±9.75)mm Hg,心率分别为(99.54±11.37)、(89.78±11.02)次/min,观察组舒张压、收缩压、心率均显著低于对照组,差异均具有统计学意义(t=8.837、6.377、3.541,P<0.05).结论 应用胺碘酮联合美托洛尔治疗快速心律失常能够有效改善患者临床症状、心电图,降低患者血压和心率水平,治疗效果显著,虽然出现轻微不良反应,但经过对症处理后均已消失,是安全有效的治疗方案.
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