目前新型冠状病毒肺炎（简称新冠肺炎）呈全球持续暴发流行趋势，作为一种急性传染病，新冠肺炎可影响全身多个器官和系统。在新冠肺炎患者中，尤其是重型和危重型患者，存在多种凝血功能障碍的潜在危险因素；此外，患者的凝血功能异常以D-二聚体水平升高为主要特征。凝血功能障碍可直接影响新冠肺炎患者预后，是重症患者死亡的重要原因之一。本文围绕新冠肺炎患者的基本临床特征、临床高危因素、凝血功能障碍发生机制及凝血功能评估进行简要综述，以期为新冠肺炎患者的临床诊治提供借鉴。“,”The coronavirus disease 2019 (COVID-19) has outbroken globally. As an acute infectious disease, COVID-19 has significant impacts on multiple organs and systems throughout the body. Among patients with COVID-19, especially severe and critical cases, a variety of potential risk factors for coagulation dysfunction exist. Furthermore, the coagulation dysfunction of COVID-19 patients was mainly characterized by elevated D-dimer levels. The coagulation dysfunction could directly affect the prognosis of COVID-19 patients and is a major cause of death in patients with severe COVID-19. In this article, the literatures on the basic clinical manifestations, clinical risk factor, mechanism of coagulation dysfunction and evaluation of coagulation function in COVID-19 were reviewed.