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目的:探讨血浆内皮素(ET)、降钙素基因相关肽(CGRP)含量变化与肺心病之间关系。方法:应用GC-1200型放射免疫γ计数仪,对120例肺心病患者在病程发展过程的含量变化与正常人进行对照。结果:肺心病患者血浆中ET含量升高CGRP含量降低,尤以急性期为著。结论:肺心病患者血中ET-1和CGRP水平与肺心病病情密切相关,是反映肺心病严重程度的标志之一。
Objective: To investigate the relationship between plasma endothelin (ET) and calcitonin gene related peptide (CGRP) levels and pulmonary heart disease. Methods: The GC-1200 radioimmunoassay gamma counter was used to compare the content of 120 patients with cor pulmonale during the development of the disease course with normal subjects. Results: Pulmonary heart disease patients with elevated plasma ET levels CGRP decreased, especially in acute phase. Conclusion: The levels of ET-1 and CGRP in the blood of patients with pulmonary heart disease are closely related to the severity of pulmonary heart disease, which is one of the markers that reflect the severity of pulmonary heart disease.