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本文用钙通道阻滞剂桂利嗪片,每次50mg,qid,治疗结肠易激综合征60例。对照组50例,用复方地芬诺酯(复方苯乙哌啶)片治疗作近期对照。桂利嗪组平均中止腹泻时间为3.8d,对照组平均12.1d,2组对照有明显差异(P<0 001)。桂利嗪组尚有明显镇痛、中止粘液便等疗效,对照组无此疗效。另对8例溃疡性结肠炎便血病人作了试治,发现桂利嗪尚有明显止血作用。其中65例减量服用该药6mo,停药1yr,总长期缓解率77％。本药副作用小,可以长期服用。
In this paper, calcium channel blocker cinnarizine tablets, each 50mg, qid, treatment of irritable bowel syndrome in 60 cases. The control group of 50 patients with diphenoxylate (compound diphenoxylate) tablets for the recent control. In the cinnarizine group, the mean time to stop diarrhea was 3.8 days, while the control group was 12.1 days on average. There was significant difference between the two groups (P <0.001). Cinnarizine group is still obvious analgesia, mucus and other effects will be stopped, the control group no such effect. The other eight cases of ulcerative colitis patients with blood in the stool were tested and found that Cinnarizine still significant hemostasis. Of which 65 cases of taking the drug reduction 6mo, withdrawal 1yr, total long-term response rate of 77%. The side effects of this drug is small, long-term use.