【摘 要】
：
MicroRNAs (miRNAs) are small RNA molecules (～21-24 nt) that play a key role in eukaryotic gene expression regulation.In plants,the majority of microRNAs are enco
【机 构】
：
Department of Gene Expression, Institute of Molecular Biology and Biotechnology, Faculty of Biology,
论文部分内容阅读
MicroRNAs (miRNAs) are small RNA molecules (～21-24 nt) that play a key role in eukaryotic gene expression regulation.In plants,the majority of microRNAs are encoded by independent transcription units transcribed by RNA polymerase Ⅱ.Primary transcripts (pri-miRNAs) of miRNA genes (MIRs) undergo extensive co-transcriptional/post-transcriptional processing to generate mature miRNAs.The main player in plant pri-miRNA processing is the microprocessor,a multiprotein complex that cleaves primiRNAs in two consecutive steps,generating the stem-loop structure containing miRNA and miRNA* (pre-miRNA) in the first step,followed by the excision of a duplex composed of miRNA/miRNA* in the second cleavage reaction.The RNA duplexes are 2O methylated at their 3ends and exported from the nucleus to the cytoplasm,where they are incorporated into the Argonaute-containing complex,RISC (RNA-induced silencing complex).miRNA* is removed while miRNA guides RISC to cognate mRNAs,leading to mRNA cleavage or translation inhibition (for review see Yu et al.,2017).
其他文献
Asign that China is quickly moving up the global service outsourcing ranking came earlier this year when EDS (Electronic Data Services), one of the worlds leadi
THE SWI/SNF COMPLEXESIn plants,as well as in metazoans,the execution of developmental programs and the response to environmental stimuli depend on changes in ge
Phototropism represents a differential growth response by which plant organs can respond adaptively to changes in the direction of incident light to optimize le
Textbook publishing was regarded as one of the top ten most profitable businesses in China for 2004and 2005. With profit margins as high as 50 percent, this is
Dear Editor,Pollen hydration is a prerequisite for pollen germination and subsequent pollen tube growth.As a result of two decades of biochemical studies and ge
Pollen tubes elongate within the pistil to transport sperm cells to the embryo sac for fertilization.Growth occurs exclusively at the tube apex,rendering pollen
Backed by the huge market size,Chinas energy companies have been ranked in the group of the worlds largest industry players. On September 6th,eight companies fr
Dear Editor,Most of the plant hormones found in flowering plants contribute to growth regulation in the moss Physcomitrella patens.This moss does not produce gi