论文部分内容阅读
人体的生物节律和某些疾病的治疗有很大的关系,在一段时间内药物的浓度不能简单地维持在恒定的水平,而必须随着生物节律的波动而波动,这种情况下,脉冲给药就能发挥它的优势。在一个24h周期内,有些生物节律表现出来的波动不止一个峰,这就需要多次脉冲给药,如胰岛素给药、化学治疗药输注、预防性疫苗接种等;虽然抗感染药物的多次脉冲给药与人体的生物节律没有关系,但是其与微生物细胞周期的联系,也是我们讨论的范畴。
The biological rhythm of the human body is strongly related to the treatment of certain diseases. The concentration of the drug over a period of time can not simply be maintained at a constant level but must fluctuate with fluctuations in the biological rhythm. In this case, the pulse Medicine can play its advantages. Some circadian rhythms show more than one peak during a 24-hour cycle, which requires multiple pulsatile doses, such as insulin, chemotherapeutic drug infusion, and prophylactic vaccinations, although multiple times of anti-infectives Pulsed administration has nothing to do with the biorhythm of the human body, but its association with the cell cycle of the microorganisms is also the domain we are discussing.