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目的：探讨中西医结合治疗早期糖尿病肾病的疗效。方法：100例患者按随机原则分为两组（各50例），治疗组在采用西药有效控制血糖水平的基础上加用具有益气养阴、活血化瘀功效的中药降糖健肾灵胶囊治疗；对照组则采用单纯西药治疗，两组均治疗3个月，并同时观察两组治疗前后症状、体征及实验室相关指标。结果：总有效率治疗组为90％，对照组为58％，两组比较有显著性差异（P＜0．05）。24h尿白蛋白排泄量，血糖，尿微量白蛋白，血、尿β2-微球蛋白及血脂，血液流变学等指标治疗组治疗后均较治疗前有显著改善（P＜0．05或P＜0．01）。结论：中西医结合治疗早期糖尿病肾病疗效明显优于单纯西药治疗。
Objective: To explore the effect of integrated traditional Chinese and western medicine on early diabetic nephropathy. Methods: One hundred patients were randomly divided into two groups (50 cases each). The treatment group was treated with the Chinese medicine Jiang Jianshenjianling Capsule, which has the effect of nourishing qi and nourishing yin and promoting blood circulation and removing blood stasis, based on the effective control of blood sugar level by western medicine While the control group was treated with western medicine alone. Both groups were treated for 3 months, and the symptoms, signs and laboratory related indicators before and after treatment were observed. Results: The total effective rate was 90% in the treatment group and 58% in the control group. There was significant difference between the two groups (P <0.05). 24h urinary albumin excretion, blood glucose, urine microalbumin, blood, urine β2-microglobulin and blood lipids, hemorheology and other indicators of treatment group after treatment than before treatment were significantly improved (P <0.05 or P <0.01). Conclusion: The treatment of early diabetic nephropathy with traditional Chinese and western medicine is superior to western medicine alone.