口腔白斑是一种发生于口腔粘膜的角化异常病损。由于它在病理上除有慢性炎症变化外,还有角化不良或/和不典型增生改变,故常被认为是一种癌前期病变。各国关于白斑恶变率的报道不一,国外报道为0.13%～10%,国内天津报道1959～1980年间收治95例口腔粘膜白斑癌变率为24.2%,因而引起人们的重视。但因其病因迄今未完全明瞭,在治疗上也缺乏有 Oral leukoplakia is a keratolytic lesion that occurs in the oral mucosa. Because of its chronic pathological changes in addition to chronic keratoses, and / or dysplasia, it is often considered a precancerous lesion. The reports on the malignancy rate of leukoplakia in various countries vary. Foreign reports ranged from 0.13% to 10%. Domestic Tianjin reported that 95 cases of oral leukoplakia cancer in the period from 1959 to 1980 were 24.2%, which attracted people’s attention. However, due to its etiology has not been fully understood so far, there is also a lack of treatment.