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目的分析SAPHO常见的临床症状、体征及特异性表现。方法回顾性分析2003年6月—2015年6月秦皇岛第一医院确诊的15例SAPHO患者的临床资料进行登记并分析。结果 15例患者均出现皮肤病变,痤疮9例,掌跖脓疱病6例,骨关节易受累的部位依次为胸锁关节(12例)、中轴关节(7例)、肩关节(5例)、腕关节(3例)。结论 SAPHO综合征患者中年女性多见,痤疮及胸锁关节滑膜炎是最常见的临床表现。
Objective To analyze the common clinical symptoms, signs and specific performance of SAPHO. Methods The clinical data of 15 patients with SAPHO diagnosed at the First Hospital of Qinhuangdao from June 2003 to June 2015 were retrospectively analyzed and registered. Results All the 15 patients had skin lesions, 9 cases of acne and 6 cases of palmoplantar pustulosis. The parts that affected the joints were thoracic joint (12 cases), axial joint (7 cases), shoulder joint (5 cases ), Wrist (3 cases). Conclusion SAPHO syndrome more common in middle-aged women, acne and sternoclavicular synovitis is the most common clinical manifestations.