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目的:观察肝痛舒口服液解痉镇痛作用。方法:采用Maguns法观察对离体兔肠的解痉作用以及用热板法观察对小鼠痛阈值的影响。结果:该药能对抗Ach和Bacl2所致的兔肠痉挛,呈明显解痉作用,并能提高小鼠痛阈值。结论:肝癌舒具有明显的解痉镇痛作用,安全、无急性毒性。
Objective: To observe the analgesic and analgesic effects of Ganotongshu oral solution. Methods: Maguns method was used to observe the antispasmodic effect on isolated rabbit intestine and the effect of hot plate on the pain threshold in mice. Results: The drug can antagonize the intestinal cramps caused by Ach and Bacl2, showed obvious antispasmodic effect and increased the pain threshold in mice. Conclusion: HCC Shu has obvious antispasmodic analgesic effect, safe, no acute toxicity.