论文部分内容阅读
大量、持续使用抗凝血灭鼠剂会使鼠类产生抗药性。为及时掌握此类药剂抗性的确切情况,我们分别于1995年和1997年调查了盐城市褐家鼠对杀鼠灵的抗药性,结果表明,1995年的致死剂量为16.19(1.17—31.21)mg/kg,没有抗性鼠存在;1997年的致死剂量为18.03(3.77—38.48)mg/kg,出现抗药性鼠,抗性鼠存活剂量为34.39(31.51—37.26)mg/kg,抗性发生率不高于6.45％,尚未形成抗药性种群,敏感鼠仍占绝对优势。因此,第一代抗凝血灭鼠剂可继续使用。
Large, continuous use of anticoagulant rodenticides will give rise to rodent resistance. In order to grasp the exact situation of the resistance of such medicaments in time, we investigated the resistance of the Rattus norvegicus to warfarin in Yancheng in 1995 and 1997 respectively. The results showed that the lethal dose in 1995 was 16.19 (1.17-31.21) mg / kg, no resistant mice were present; the lethal dose was 18.03 (3.77-38.48) mg / kg in 1997, the resistant mice appeared, and the surviving dose of resistant mice was 34.39 (31.51-37.26) mg / kg, Rate of not higher than 6.45%, has not yet formed a drug-resistant populations, sensitive rats still occupy an absolute advantage. Therefore, the first generation of anticoagulant rodenticides can continue to be used.