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目的分析医院抗抑郁药的应用状况,为临床合理用药提供依据。方法采用限定日剂量为指标,对医院2009-2011年常用抗抑郁药的数据进行统计分析,对用药金额和用药频度(DDDs)进行排序。结果医院抗抑郁药的用药金额及DDDs均逐年提高。结论医院使用抗抑郁药用量逐年递增,5-羟色胺再摄取抑制药(SSRIs)类占主导地位,文拉法辛、度洛西汀等新型抗抑郁药应用前景广阔。
Objective To analyze the application of antidepressants in hospitals and provide the basis for clinical rational use of drugs. Methods Using the limited daily dose as an index, the data of commonly used antidepressants in the hospital from 2009 to 2011 were statistically analyzed, and the dosage and frequency of drug use (DDDs) were ranked. Results The amount of hospital antidepressants and DDDs increased year by year. Conclusions The amount of antidepressant used in hospitals increases year by year, and serotonin reuptake inhibitors (SSRIs) dominate. The new antidepressants such as venlafaxine and duloxetine have a bright future.