鼻咽癌是我国南方常见的恶性肿瘤,通过综合治疗其5年生存率在50%～60%。p73基因是Kaghad等〔1〕在COS细胞cDNA文库中利用TRS21结合区和互补寡核苷酸杂交中偶然发现的,定位于人染色体1p36.2-36.3。研究表明p73 Nasopharyngeal carcinoma is a common malignant tumor in southern China, and its 5-year survival rate is 50% -60% through comprehensive treatment. p73 gene is Kaghad et al 〔1〕 in the COS cell cDNA library by TRS21 binding region and complementary oligonucleotide hybridization accidentally located in the human chromosome 1p36.2-36.3. Research shows that p73