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采用酶联免疫吸附法检测了19例结核性和18例癌性胸膜炎患者血清和胸水中sIL-2R水平。结果:结核组血清sIL-2R(739.6±503.2KU/L)明显高于正常组(255.1±99.7KU/L)和癌性组(219.6±184.6KU/L)(P均<0.01),而癌性组与正常组比较差异无显著性意义(P>0.05);结核组胸水sIL-2R(1598.7±1153.6KU/L)明显高于癌性组(804.9±426.1KU/L)(P<0.01)。若以血清sIL-2R455KU/L为界限值,则结核组的敏感性63.2%,特异性为83.3%;以胸水sIL-2R1230KU/L为界限值,则结核组的敏感性为68.4%,特异性88.9%,提示血清、胸水sIL-2R测定对鉴别这两组胸膜炎有较高的价值,可作为鉴别结核性和癌性胸膜炎的一项检测指标。
Serum and pleural fluid levels of sIL-2R were measured in 19 tuberculous and 18 cancerous pleurisy patients by enzyme-linked immunosorbent assay. Results: Serum sIL-2R (739.6 ± 503.2KU / L) in tuberculosis group was significantly higher than that in normal group (255.1 ± 99.7KU / L) and cancerous group (219.6 ± 184.6KU / L) (P <0.01), while there was no significant difference between the cancerous group and the normal group (P> 0.05). The sIL-2R level in the tuberculosis group was significantly higher than that of the sIL-2R group (1598.7 ± 1153.6KU / L) Cancerous group (804.9 ± 426.1KU / L) (P <0.01). If the serum sIL-2R455KU / L as the limit, the sensitivity of the tuberculosis group was 63.2% and the specificity was 83.3%; the pleural fluid sIL-2R1230KU / L was the threshold value, the sensitivity of the tuberculosis group was 68 .4%, specificity of 88.9%, suggesting that serum, pleural fluid sIL-2R determination of the differential diagnosis of these two groups of pleurisy has a higher value, can be used as a test to identify tuberculous and cancerous pleurisy.