天津市南开医院肝胆胰外科二收治1例首先表现为双下肢散在结节性脂膜炎,后经影像学检查后考虑胰腺巨大占位性病变,并与双下肢脂膜炎密切相关的罕见病例.手术治疗后,标本病理提示:腺泡细胞癌,患者原发疾病治愈,双下肢散在脂膜炎好转.本病实属罕见,特报道此病例. Tianjin Nankai Hospital, hepatobiliary and pancreatic surgery two cases of 1 case first manifested as double-lower extremity scattered nodular panniculitis, after imaging examination of the huge occupying lesions of the pancreas and double-limb Paniculitis and rare cases Surgical treatment, the specimen pathology prompted: acinar cell carcinoma, the patient’s primary disease cured, double lower extremity scattered panniculitis improved. The disease is rare, especially reported in this case.