多胺是指腐胺,尸胺、精脒和精胺等一类的小分子脂肪族非蛋白质含氮化合物,是机体重要的代谢调控物质。恶性肿瘤组织的生长代谢特别旺盛,从而导致体液中多胺增加,1971年Russell首先发现恶性肿瘤患者尿中多胺明显高于健康人,以后国内外相继有这方面的研究报道,比较一致认为可作肿瘤诊断、疗效评价的一项生化指标。 材料与方法:我科对179例经确诊恶性肿瘤患者收集24小时尿作多胺测定。患者中以鼻咽癌、肺癌,食管癌、恶性淋巴瘤为主,高效液相色谱仪系 Polyamines are small-molecule, aliphatic, non-proteinaceous, nitrogen-containing compounds such as putrescine, cadaverine, spermidine, and spermine, which are important metabolic regulators in the body. Malignant tumors are particularly prosperous in their growth and metabolism, resulting in an increase in polyamines in body fluids. In 1971, Russell first discovered that polyamines in patients with malignant tumors were significantly higher than those in healthy people. Later studies at home and abroad have reported in this area. As a biochemical indicator of tumor diagnosis and efficacy evaluation. Materials and Methods: Our department collected 179 cases of diagnosed malignant tumors and collected 24-hour urinary polyamines. Among the patients, nasopharyngeal carcinoma, lung cancer, esophageal cancer, and malignant lymphoma were the main components.