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目的观察山东省肥城市食管癌高发区人群不同食管部位患病情况,为病因学研究提供科学依据。方法碘染色内镜检查食管黏膜,不染色区域取活检,经病理学诊断食管各种病变情况。结果普查有效资料9526人,取活检经病理诊断1418例,其中食管上段337例,上中交界63例,中段560例,中下交界64例,下段394例;发现食管上段、中段、下段食管癌分别为34,66,35例;将性别、年龄、文化水平、家庭人均收入作为调整因素,发现食管癌家族史、吸烟、饮酒对食管不同部位病变有不同程度的影响,其中对中段食管疾病的影响最为明显。结论食管中段是食管病变的好发部位,受各种危险因素的影响最大,需进一步研究不同部位食管癌的危险因素。
Objective To observe the prevalence of different esophageal sites in the high-incidence area of esophageal cancer in Feicheng City, Shandong Province, and provide scientific basis for etiological study. Methods Esophageal mucosa was endoscopically stained with iodine staining. Biopsy was performed on the non-stained area. Esophageal lesions were diagnosed by pathology. RESULTS: There were 9526 census data, and 1418 cases were biopsy pathologically diagnosed, including 337 cases in the upper esophagus, 63 cases in the upper-middle border, 560 cases in the middle segment, 64 cases in the mid-lower border, and 394 cases in the lower segment. Esophageal cancer was found in the upper, middle, and lower esophagus. 34, 66, and 35 cases respectively; gender, age, education level, and household per capita income were used as adjustment factors to find that family history of esophageal cancer, smoking, and alcohol consumption had different degrees of influence on different parts of esophageal lesions, among which were intermediate esophageal diseases. The most obvious effect. Conclusions The middle esophagus is a predilection site of esophageal lesions, which is the most affected by various risk factors. It is necessary to further study the risk factors of esophageal cancer in different sites.