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近年来抗菌素虽已得到普遍应用,但由于有时能引致过敏反应以及細菌抗药性的产生,它們在临床上並不能完全取代磺胺类药物的地位,而是起着相互补充的作用。直到不久以前,常用的磺胺类药物如磺胺噻唑和磺胺嘧啶等有一个共同缺点,就是較易从体內排出,因而在一个疗程中必须按时經常服用,以維持其在血液中的有效濃度缫话阍诘谝淮畏?克,以后就須要不分晝夜地每4小时服用1克,这种服用方法自然給病人带来很大麻煩虬芳谆奏ず突前范奏奏ぴ谡夥矫嫠淙挥兴慕?但差別不大。为此,近年来在長效磺胺药物的寻找方面作了许多研究工作,而磺胺
Although antibiotics have been widely used in recent years, they can sometimes cause allergic reactions and the development of bacterial resistance. They do not completely replace the status of sulphonamides in clinical practice, but play a complementary role. Until recently, commonly used sulfa drugs such as sulfathiazole and sulfamethazine had a common defect that they were more easily excreted from the body, so they must be taken regularly and regularly in a course of treatment to maintain its effective concentration in the blood. If you want to take 1 g of it every 4 hours, it will naturally cause great trouble for the patient. Do you know what you want to do? However, the difference is not great. For this reason, many researches have been done in the search for long-acting sulfa drugs in recent years.