Comparison of Clinical Efficacy of Three Surgical Methods in the Treatment of Pterygium

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Purpose:To investigate and compare the efficacy of amniotic membrane transplantation,corneal limbus stem cell conjunctival transplantation and pedicle conjunctival flap transposition in the treatment of pterygium.Methods:.A total of 155 patients with pterygium were retrospectively analyted:.53 cases who received amniotic membrane transplantation,.41 who underwent corneal limbus stem cells conjunctival transplantation,and 61 patients who had pedicle conjunctival flap transposition.Results:Patients in the three groups had no significant differences in terms of age,times since surgery,or extent of pterygium extension onto the cornea (F:1.194,0.639,0.140 respectively;all P>0.05)..A total of 137 out of 155 patients (88.4%) completed 6 months of follow up.The recurrence rates of pterygium for the three surgeries (amniotic membrane transplantation,.corneal limbus stem cells conjunctival transplantation and pedicle conjunctival flap transposition) were 14.6%,13.9% and 7.7%,respectively.No significant difference was identified when comparing the recurrence rate between any two groups(X2:.0.008,1.211 and 0.890;P:0.593,0.218 and 0.276)..Five patients presented with postoperative complications,.including 3 cases of sub-conjunctival hemorrhage,1 case of amniotic membrane dissolution,and 1 case of conjunctival cyst,accounting for 3.64% of all participants.Conclusion:These three surgical methods are equally effective in preventing the recurrence of pterygium after excision. Purpose: To investigate and compare the efficacy of amniotic membrane transplantation, corneal limbus stem cell conjunctival transplantation and pedicle conjunctival flap transposition in the treatment of pterygium. Methods:. A total of 155 patients with pterygium were retrospectively analyzed: .53 cases who received amniotic membrane transplantation, .41 who underwent corneal limbus stem cells conjunctival transplantation, and 61 patients who had pedicle conjunctival flap transposition. Results: Patients in the three groups had no significant differences in terms of age, times since surgery, or extent of pterygium extension onto the cornea (F: 1.194, 0.639, 0.140 respectively; all P> 0.05). A total of 137 out of 155 patients (88.4%) completed 6 months of follow up. The recurrence rates of pterygium for the three surgeries (amniotic membrane transplantation, .corneal limbus stem cells conjunctival transplantation and pedicle conjunctival flap transposition) were 14.6%, 13.9% and 7.7% respectively. No sign ificant difference was identified when comparing the recurrence rate between any two groups (X2: .0.008, 1.211 and 0.890; P: 0.593, 0.218 and 0.276) .. Five patients presented with postoperative complications, .including 3 cases of sub-conjunctival hemorrhage, 1 case of amniotic membrane dissolution, and 1 case of conjunctival cyst, accounting for 3.64% of all participants. Confluence: These three surgical methods are equally effective in preventing the recurrence of pterygium after excision.
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