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目的:探讨心脏死亡器官捐献(DCD)供者肾移植的临床效果。方法:回顾性分析发生急性肾衰竭(ARF)的DCD供者肾移植临床资料。结果:来自15例ARF供者的30个肾脏植入29例受者体内(其中1例接受双肾移植)。供体起始和终末血清肌酐分别为90.1±35.1μmol/L和355.6±153.1μmol/L。术后8例(27.6%)受者发生移植肾功能延迟恢复,随访2~21月,人肾存活率均为100%。术后1月和12月肾小球滤过率分别为55.5±10.5 ml/(min·1.73m2)和60.8±10.6 ml/(min·1.73m2)。结论:DCD供者肾移植术后的近期效果良好,是扩大供肾来源的潜在途径。
Objective: To investigate the clinical effect of donor kidney donation (DCD) donor kidney transplantation. Methods: The clinical data of renal transplant recipients with acute renal failure (ARF) on DCD were retrospectively analyzed. RESULTS: Thirty of the 15 kidneys from 15 ARF donors were implanted in 29 recipients (1 of them underwent renal transplantation). Serum creatinine at the start and end of the donor were 90.1 ± 35.1 μmol / L and 355.6 ± 153.1 μmol / L, respectively. Postoperatively, 8 patients (27.6%) had delayed graft function recovery. The survival rate of human kidney was 100% at 2 to 21 months follow-up. Glomerular filtration rates at 1 month and 12 months after operation were 55.5 ± 10.5 ml / (min · 1.73 m 2) and 60.8 ± 10.6 ml / (min · 1.73 m 2), respectively. CONCLUSION: The immediate effect of DCD donor kidney transplantation is good, which is a potential way to expand the source of donor kidney.