Synthesis, Mechanism of Formation and Insecticidal Activity of Novel Fluorinated Organophosphorus Co

来源 :Chinese Journal of Chemistry | 被引量 : 0次 | 上传用户:fightwang
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The major products of the interaction between triethyl phosphite and 3-fluoropropanoyl chloride at room temperature are diethyl (E)-1-(3-fluoropropanoyloxy)-3-fluoroprop-1-enyl-phosphonate (3) and diethyl 1-(diethoxyphosphoryl)-3-fluoropropyl phosphate (4). The compounds 3 and 4 were separated by chromatography, and structurally characterized by elemental analysis, NMR spectroscopy ( 1H, 13C, 19F and 31P) and mass spectrometry. Possible reaction mechanisms are proposed. The major products 3 and 4 were tested for insecticidal activity. 3 gave 100% control of Musca domestica L. and Phaedon cochledriae Fab. at a dose of 20 μg/per insect. The major products of the interaction between triethyl phosphite and 3-fluoropropanoyl chloride at room temperature are diethyl (E) -1- (3-fluoropropanoyloxy) -3-fluoroprop-1-enyl- phosphonate (3) and diethyl 1- 3-fluoropropyl phosphate (4). The compounds 3 and 4 were separated by chromatography, and structurally characterized by elemental analysis, NMR spectroscopy (1H, 13C, 19F and 31P) and mass spectrometry. 3 and 4 were tested for insecticidal activity. 3 gave 100% control of Musca domestica L. and Phaedon cochledriae Fab. At a dose of 20 μg / per insect.
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