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儿童风湿病是一组自身免疫性疾病,主要累及结缔组织和血管。由于肺脏具有丰富的结缔组织和血管,风湿病常伴有肺间质病变,预后极差。儿童风湿病更易发生肺间质病变,而且以亚临床型多见,但能通过影像学等检查早期发现,及时治疗可改善预后。现主要介绍儿童风湿病相关性肺间质病变的流行病学、临床表现、诊断、影像学表现和病理基础、治疗及预后。
Childhood rheumatism is a group of autoimmune diseases that mainly involve connective tissue and blood vessels. As the lungs are rich in connective tissue and blood vessels, rheumatism is often accompanied by interstitial lung disease, the prognosis is poor. Child rheumatoid disease more prone to interstitial lung disease, but more common in subclinical, but can detect early detection by imaging and timely treatment can improve the prognosis. Epidemiology, clinical manifestations, diagnosis, imaging findings and pathological basis, treatment and prognosis of rheumatoid arthritis-related pulmonary interstitial lesions in children are mainly introduced.