论文部分内容阅读
目的:探讨体外受精-胚胎移植(IVF-ET)患者注射人绒毛膜促性腺激素(HCG)日血清孕酮(P)水平对IVF-ET妊娠结局的影响。方法:回顾性分析我中心2008～2009年经过IVF-ET治疗后行胚胎移植术的患者1416个周期的临床资料。根据注射HCG日血清P水平,分为P<2ng/ml(A组),2ng/ml≤P<3ng/ml(B组),P≥3ng/ml(C组),比较各组患者年龄、不孕年限、内膜厚度、窦卵泡数、获卵数、胚胎数、优胚数、移植胚胎数、种植率和临床妊娠率。结果:各组患者年龄、不孕年限、内膜厚度、窦卵泡数、获卵数、胚胎数、优胚数、移植胚胎数均无显著性差异。A组种植率为27.81%、临床妊娠率为42.89%;B组种植率为22.36%、临床妊娠率为36.48%;C组种植率为15.96%、临床妊娠率为27.27%,各组比较有显著性差异。结论:IVF-ET中,注射HCG日血清P水平升高可引起临床妊娠率和种植率的下降。
Objective: To investigate the effect of serum progesterone (P) on the pregnancy outcome of IVF-ET in patients with IVF-ET injected with human chorionic gonadotropin (HCG). Methods: The clinical data of 1416 patients who underwent embryo transfer after IVF-ET treatment in our center from 2008 to 2009 were retrospectively analyzed. According to the level of serum P on the day of HCG injection, the patients were divided into two groups: group A (P <2ng / ml), group B (2ng / ml≤P <3ng / Infertility duration, endometrial thickness, antral follicles, number of retrieved ova, number of embryos, number of excellent embryos, number of embryos transferred, implantation rate and clinical pregnancy rate. Results: There were no significant differences in age, length of infertility, intima thickness, number of antral follicles, number of oocytes retrieved, number of embryos, number of excellent embryos and number of embryos transferred in each group. The implantation rate in group A was 27.81% and the clinical pregnancy rate was 42.89%. The implantation rate in group B was 22.36% and the clinical pregnancy rate was 36.48%. The implantation rate in group C was 15.96% and the clinical pregnancy rate was 27.27% Sex differences. CONCLUSION: In IVF-ET, the increase of serum P level on HCG injection can cause the decline of clinical pregnancy rate and implantation rate.