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中枢神经轴突外微环境包括胶质细胞及化学因子,中枢神经系统损伤后修复的成功依赖于损伤的神经通路中至少有一部分存活的神经元和适当的微环境。本文综述成年哺乳动物轴突外微环境的研究进展。 1 胶质细胞 CNS中的胶质细胞是大胶质细胞(星形胶质细胞、少突胶质细胞)和小胶质细胞,其中星形胶质细胞造成的胶质瘢痕最早引起注意和研究。为了避免形成或减缓形成胶质瘢痕,先后采用过多种方法:①
The extranodal microenvironment of the central nervous system includes glial cells and chemokines. The success of repair following central nervous system injury relies on at least some of the surviving neurons and proper microenvironment in the injured nerve pathways. This review summarizes the research progress on the microenvironment of adult mammalian axons. Glial cells in glial cells CNG is a large number of glial cells (astrocytes, oligodendrocytes) and microglia, glial scar caused by astrocytes earliest attention and research . In order to avoid the formation or slow down the formation of glial scar, has adopted a variety of methods: ①