目的观察BiPAP呼吸机治疗急性呼吸衰竭的疗效。方法对30例急性呼吸衰竭患者进行双水平(BiPAP)呼吸机治疗,观察治疗前后血气及症状休征的变化。结果治疗后26例患者PaO2、SaO2、pH升高,R、HR、PaCO2、HCO3下降,患者症状改善。4例病人治疗无效改为有创通气。结论无创通气对人部分COPD合并呼吸衰竭的病人有效,但需选择合适的适应证,必要时及时改用有创通气。 Objective To observe the efficacy of BiPAP ventilator in the treatment of acute respiratory failure. Methods Thirty patients with acute respiratory failure were treated with BiPAP and the changes of blood gas and symptoms before and after treatment were observed. Results After treatment, the PaO2, SaO2, pH, R, HR, PaCO2 and HCO3 in 26 patients decreased, and their symptoms improved. 4 cases of invalid treatment to invasive ventilation. Conclusion Noninvasive ventilation is effective in patients with partial COPD and respiratory failure. However, appropriate indications should be selected and, if necessary, timely use of invasive ventilation.