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目的探讨老年急性心力衰竭患者血清N末端脑钠肽原(NT-pro BNP)水平及急性生理与慢性健康评分(APACHEⅡ评分)与预后的相关性。方法选取2013年1月至2015年12月老年急性心力衰竭患者60例,采用APACHEⅡ评分对患者进行评估,检测患者血清NT-pro BNP水平,根据APACHEⅡ评分将患者分为<10分组、≥10分组,比较两组的NT-pro BNP水平。根据患者的死亡情况将患者分为死亡组和存活组,比较两组患者的NTpro BNP水平、APACHEⅡ评分,计算NT-pro BNP水平、APACHEⅡ评分与老年急性心力衰竭患者预后的相关性系数。结果≥10分组的NT-pro BNP水平较<10分组明显更高(P<0.05)。与存活组相比,死亡组的NT-pro BNP水平、APACHEⅡ评分均明显更高(P<0.05)。NT-pro BNP水平、APACHEⅡ评分与老年急性心力衰竭患者的预后密切相关。结论老年急性心力衰竭患者的NT-pro BNP水平、APACHEⅡ评分与其预后之间存在相关性,临床上可采用NT-pro BNP水平、APACHEⅡ评分来预测老年急性心力衰竭患者的预后。
Objective To investigate the correlation between serum N-terminal pro-brain natriuretic peptide (BNP) level, acute physiology and chronic health score (APACHEⅡ score) and prognosis in elderly patients with acute heart failure. Methods Sixty elderly patients with acute heart failure from January 2013 to December 2015 were selected. APACHEⅡscore was used to evaluate the level of serum NT-pro BNP in patients. According to APACHEⅡscore, the patients were divided into 10 groups and 10 groups The levels of NT-pro BNP in both groups were compared. The patients were divided into death group and survival group according to their death. The correlation between NTpro BNP level, APACHEⅡscore, NT-pro BNP level and APACHEⅡscore in elderly patients with acute heart failure were compared. Results The level of NT-pro BNP≥10 was significantly higher than that of <10 group (P <0.05). Compared with the survival group, NT-pro BNP level and APACHEⅡ score in death group were significantly higher (P <0.05). NT-pro BNP levels, APACHE Ⅱ score and the prognosis of elderly patients with acute heart failure are closely related. Conclusion There is a correlation between NT-pro BNP level and APACHEⅡscore in elderly patients with acute heart failure. Prognosis of elderly patients with acute heart failure may be predicted by using NT-pro BNP level and APACHEⅡscore.