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SAV联合化疗药物喜树碱、阿糖胞苷治疗S180瘤小鼠的实验中,对每种药物分设3种剂量,并分别通过肌肉、腹腔、皮下3种途径给药,观察60d内的小鼠平均存活时间。结果表明,SAV与化疗药物联合应用的效果最佳,小鼠平均存活期达57Experimentlstudyonthetherapeuticeffectivenessontumor活期为49.29±8.08d,仅用阿糖胞苷时,小鼠平均存活期为50.2±8.06d。本实验采用了析因试验统计,表明用析因试验统计具有获得较多的信息和节约动物等优点。
SAV combined with chemotherapeutic drugs camptothecin, cytarabine in the treatment of S180 tumor mice, divided into three doses for each drug, and administered through the muscle, celiac, subcutaneous three routes, observed mice within 60d Average survival time. The results showed that the combination of SAV and chemotherapeutic drugs had the best effect. The average survival time of mouse was 57 Experimentlstudyonthetherapeuticeffectivenessontumor. The survival time was 49.29±8.08d. When using cytarabine alone, the average survival time of mice was 50.2±8.06d. In this experiment, factorial test statistics were used to show that using factorial test statistics has the advantages of obtaining more information and saving animals.