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目的对比分析冠心病(CHD)合并糖调节受损(IGR)或2型糖尿病(T2DM)患者冠状动脉特点及介入术后观察。方法选择CHD患者1212例,按WHO诊断标准分为血糖正常(NGT)组、空腹血糖受损(IFG)组、糖耐量受损(IGT)组及T2DM组,比较各组问冠状动脉病变程度及介入术后支架内再狭窄和晚期血栓的发生率。结果糖代谢异常各组在冠状动脉狭窄程度、病变范围、病变性质等方面的积分显著高于NGT组(P<0.05或P<0.01)。糖代谢异常患者支架内再狭窄率及T2DM患者晚期血栓形成率均显著增高(P<0.01)。结论 CHD合并IGR或T2DM患者,多个CHD危险因素并存,冠状动脉多支病变多见,病变程度严重、弥漫,且支架内再狭窄率及晚期支架内血栓形成率高。
Objective To compare and analyze the characteristics of coronary artery in patients with coronary heart disease (CHD) complicated with impaired glucose regulation (IGR) or type 2 diabetes mellitus (T2DM) and to observe the characteristics of coronary artery. Methods 1212 CHD patients were selected and divided into three groups according to WHO diagnostic criteria: normal blood glucose (NGT) group, impaired fasting glucose (IFG) group, impaired glucose tolerance (IGT) group and T2DM group. The rate of in-stent restenosis and late thrombosis after interventional procedure. Results The abnormal glucose metabolism in each group in the degree of coronary artery stenosis, lesions, lesions and other aspects of the score was significantly higher than NGT group (P <0.05 or P <0.01). Patients with abnormal glucose metabolism in the stent restenosis rate and T2DM patients with advanced thrombosis were significantly higher (P <0.01). Conclusion CHD combined with IGR or T2DM patients, multiple CHD risk factors coexist, multiple coronary lesions more common, severe degree, diffuse, and in-stent restenosis rate and late stent thrombosis rate.