论文部分内容阅读
目的观察70岁以上老年食管癌三维适形放疗的临床疗效和副反应。方法 45例食管癌患者均采用三维适行放疗,肿瘤剂量50~62 Gy。结果 45例老年食管癌患者放疗后完全缓解(CR)17例(37.8%),部分缓解(PR)24例(53.3%),有效率91.1%(41/45)。1,2年生存率分别为68.8%和37.8%。死亡原因中局部复发15例,占53.6%;远处转移7例,占25.0%。结论三维适形放射治疗老年食管癌对缓解症状、提高生存质量起到了积极作用,放射性肺炎的发生与老年人基础疾病有关。
Objective To observe the clinical efficacy and side effects of three-dimensional conformal radiotherapy for elderly patients with esophageal cancer over 70 years old. Methods 45 cases of esophageal cancer patients were treated with appropriate three-dimensional radiotherapy, tumor dose 50 ~ 62 Gy. Results Among the 45 elderly patients with esophageal cancer, complete remission (CR) was achieved in 17 cases (37.8%) and partial remission (PR) in 24 cases (53.3%). The effective rate was 91.1% (41/45). The 1-year and 2-year survival rates were 68.8% and 37.8% respectively. Local causes of death in 15 cases, accounting for 53.6%; distant metastasis in 7 cases, accounting for 25.0%. Conclusion Three-dimensional conformal radiotherapy for elderly patients with esophageal cancer has a positive effect on alleviating the symptoms and improving the quality of life. The incidence of radiation pneumonitis is related to the underlying diseases of the elderly.