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牛黄解毒片是一临床常用的清热解毒药,对其引起过敏的报道少见。笔者近遇一口服该药致固定型药疹的病例,现报告如下: 患者王×,男,卫生员。因咽痛于85年5月17日、18日自服牛黄解毒片各2片,(兰州中药制药厂生产),再未应用其它药物。19日晨觉双踝关节处皮肤痒痛,局部微红,即停服该药。20日因灼痒加剧就诊。查体见一般情况好,右内、外躁,左内踝等处皮肤有约3×4厘米大小的椭园形红斑三块,局部水肿发亮,边缘清楚,无渗出及糜烂。诊断为固定型药疹。给于扑尔敏24毫克/日,维生索C1.2
Bezoar detoxification film is a commonly used clinical detoxification drugs, allergic reactions caused by rare reports. The author received a case of drug-induced fixed-type drug eruption, are reported as follows: Patient Wang ×, male, health workers. Due to sore throat in 85 May 17, 18 self-serving bezoar detoxification tablets each 2, (Lanzhou Chinese medicine factory production), then no other drugs. On the morning of the 19th, the both ankle joints were found with itchy skin and reddish locally, stopping taking the medicine. On the 20th due to itching intensified treatment. See the general situation of good physical examination, the right internal and external manicure, the left medial malleolus and other parts of the skin about 3 × 4 cm in size oval erythema three, local edema shiny, clear edge, no exudation and erosion. Diagnosis of fixed drug eruption. To chlorpheniramine 24 mg / day, vitamins C1.2