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目的探讨正电子发射计算机体层成像(PET/CT)与高分辨率CT(HRCT)在孤立型细支气管肺泡癌(sol-itary bronchioloalveolar carcinoma,SBAC)诊断中协同应用的价值,以提高对该病的诊断准确率。方法搜集经手术病理证实的28例SBAC患者的PET/CT及HRCT影像资料,患者均先行PET/CT显像,其中16例根据诊断需要于0～3天内行HRCT检查,分析两者对SBAC的协同诊断价值。结果 28例中,PET/CT显像确切诊断肺癌者15例(53.6%),恶性不除外5例(17.9%),良性病变8例(28.6%),误诊率较高。16例HRCT协同PET/CT确切诊断肺癌15例,其中1例初诊良性病变,后经HRCT结合图像后处理技术诊断为肺癌,1例伴右肺门淋巴结转移者,HRCT图像仅显示形态正常淋巴结影,而PET/CT诊断淋巴结转移,后经病理证实;PET/CT与HRCT协同诊断正确率达100%。结论 PET/CT显像诊断SBAC易出现假阴性,误诊率较高;PET/CT与HRCT在SBAC诊断中的协同应用能够弥补常规PET/CT显像中的不足,达到优势互补并充分发挥PET/CT的资源优势,有助于提高对SBAC的诊断准确率。
Objective To investigate the value of PET / CT and HRCT in the diagnosis of solitary bronchioloalveolar carcinoma (SBAC) The diagnostic accuracy. Methods PET / CT and HRCT images of 28 patients with SBAC confirmed by surgery and pathology were collected. All patients underwent PET / CT imaging. Among them, 16 patients underwent HRCT examination within 0 to 3 days according to the diagnosis needs, Collaborative diagnostic value. Results Of the 28 cases, PET / CT imaging confirmed the diagnosis of lung cancer in 15 cases (53.6%), 5 cases (17.9%) without malignancy and 8 cases (28.6%) in benign lesions. The misdiagnosis rate was high. 16 cases of lung cancer were diagnosed by HRCT and PET / CT in 15 cases. One case had newly diagnosed benign lesion. HRCT combined with image postprocessing diagnosed lung cancer and 1 case with right hilar lymph node metastasis. The HRCT images showed only morphologically normal lymph nodes , While PET / CT diagnosis of lymph node metastasis, confirmed by pathology; PET / CT and HRCT collaborative diagnosis rate of 100%. Conclusions PET / CT imaging is a false negative for diagnosis of SBAC, and its misdiagnosis rate is high. The synergistic application of PET / CT and HRCT in the diagnosis of SBAC can make up for the deficiencies in conventional PET / CT imaging, complement each other and give full play to PET / CT’s resource advantages, help to improve the diagnostic accuracy of SBAC.